CRITICAL ANALYSIS OF THE EFFICACY AND LIMITATIONS OF GLP-1 PHARMACEUTICALS IN OBESITY MANAGEMENT: A COMPREHENSIVE LITERATURE REVIEW

Introduction and purpose Obesity, a pervasive global pandemic intricately linked to various comorbidities, necessitates a comprehensive and nuanced approach.This article delves into the intricate realm of obesity guidelines, underscoring the significance of lifestyle modifications, preventive measures for childhood obesity, population-based strateg

Calcineurin plays a key role in morphogenesis, pathogenesis and drug resistance in most fungi.However, the function of calcineurin genes in Puccinia striiformis f.sp.tritici (Pst) is unclear.We identified and characterized the calcineurin genes PsCNA1 and PsCNB1 in Pst.Phylogenetic analyses Mask indicate that PsCNA1 and PsCNB1 form a calcium/calmod